Diet Induced Type Ii Diabetes In C57bl 6j Mice
Twenty animals from each strain received ad libitum exposure to a high fat high simple carbohydrate diet or standard purina rodent chow for 6 mo. Looking for diet induced type 2 diabetes in c57bl 6j mice.
diet induced type ii diabetes in c57bl 6j mice
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We investigated the effects of diet induced obesity on glucose metabolism in two strains of mice c57bl6j and aj.
Diet induced type ii diabetes in c57bl 6j mice. Artemisia herba alba or centaurium erythraea extracts reduced plasma glucose insulin triglycerides and total cholesterol concentrations in c57bl6j mice with high fat diet induced type 2 diabetes. We investigated the effects of diet induced obesity on glucose metabolism in two strains of mice c57bl6j and aj. We have previously shown that c57bl6j b6 mice develop severe obesity and diabetes if weaned onto high fat diets whereas aj mice tend to be obesity and diabetes resistant.
From the moment you are identified with type 2 diabetes you are most likely to be confronted with what looks like an endless list of new tasks medical consultations taking medication stopping smoking cigarettes being more active and eating a healthy balanced diet plan. For murine model of diet induced type 2 diabetes male c57bl6j mice are used. Revision received april 5 1988.
Received february 16 1988. Exposure to the high fat high simple diet induced type ii diabetes in c57bl6j mice diabetes. Exposure to the high fat high simple carbohydrate low fiber diet produced obesity in both aj and c57bl6j mice.
Female c57bl6j mice were fed a high fat diet 58 energy by fat or a normal diet 11 fat. These data suggest that the c57bl6j mouse carries a genetic predisposition to develop non insulin dependent type ii diabetes. I have type 2 diabetes what can i eat.
The purpose of this study was to determine if obesity and diabetes in the b6 mouse could be completely reversed by reducing dietary fat content. We investigated the effects of diet induced obesity on glucose metabolism in two strains of mice c57bl6j and aj. This study characterizes the high fat dietfed mouse as a model for impaired glucose tolerance igt and type 2 diabetes.
Twenty animals from each strain received ad libitum exposure to a high fat high simple carbohydrate diet or standard purina rodent chow for 6 mo. Futhermore altered glycemic response to adrenergic stimulation may be a biologic marker for this genetic predisposition to develop type ii diabetes. The standard study design includes 7 days of acclimatization period 20 weeks of diet induced weight gain period 5 days for diabetes verification 14 days of treatment period and 7 days of post treatment observation.
Twenty animals from each strain received ad libitum exposure to a high fat high. This conforts the traditional use of these plants in human established type 2 diabetes mellitus. Diet induced type ii diabetes in c57bl6j mice.
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